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Virolans (Nevirapine)
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Virolans

Virolans belongs to the class of antiretroviral medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It is used in combination with other antiretroviral medications to treat the infection caused by the human immunodeficiency virus (HIV).

Other names for this medication:
Cytocom, Duovir, Emduo, Emtri, Lamostad, Lazid, Nevilast, Nevimune, Nevipan, Nevir, Nevirapine, Neviraprine, Neviretro, Nevirex, Nevivir, Nexvir, Stavex, Trimune, Triomune, Trivir, Virocomb, Virolans, Zidolam

Similar Products:
Coumadin, Zanaflex, Pepcid, Dulcolax, Silagra, Differin, Neviretro, Wormorid, Diamet, Gester, Ezibloc, Nifedine, Alpranex, Lotim,

Also known as: Nevirapine

Description

Nevirapine is used in combination with other medicines for the treatment of the infection caused by human immunodeficiency virus (HIV). HIV is the virus that causes acquired immune deficiency syndrome (AIDS).

Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It works by lowering the amount of HIV in the blood.

Nevirapine will not cure HIV infection or AIDS, however, it helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay the development of problems that usually result from AIDS or HIV disease. Nevirapine will not keep you from spreading HIV to other people. People who receive this medicine may continue to have some of the problems usually related to AIDS or HIV disease.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain nevirapine. It may not be specific to Virolans O/S. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Also, do not change the dose or stop using this medicine without checking first with your doctor. When your supply of this medicine is running low, contact your doctor or pharmacist ahead of time. Do not allow yourself to run out of this medicine.

This medicine comes with a Medication Guide. Read and follow these instructions carefully before starting nevirapine treatment and each time you refill your prescription. Ask your doctor if you have any questions.

Nevirapine may be taken with or without food, and with water, milk, or soda.

If you or your child are taking the oral liquid, shake it gently before use. Use an oral dosing syringe or dosing cup to measure the right dose. After drinking the medicine, rinse the dosing cup with water and drink the water to make sure you get all of the medicine. If your dose is less than 5 mL (one teaspoonful), use the dosing syringe.

Swallow the extended-release tablet whole. Do not crush, break, or chew it.

Keep taking nevirapine for the full time of treatment, even if you or your child begin to feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

It is important to take nevirapine as part of a combination treatment. Take all other medicines your doctor has prescribed at the right time of the day. This will make your medicines work better.

This medicine works best when there is a constant amount in the blood. To help keep blood levels constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times during the day. For example, if you or your child are taking one dose per day, try to take it at the same time each day. If you are taking two doses per day, the doses should be spaced about 12 hours apart. If you need help planning the best times to take your medicine, check with your doctor.

Do not take more than one dosage form of nevirapine at the same time. Talk to your doctor if you have any questions.

If you stop taking this medicine for more than 7 days, ask your doctor how much to use before you start taking it again. .

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of HIV infection: For oral dosage form (extended-release tablets): Adults—At first, one 200 milligram (mg) Virolans® immediate-release tablet once a day for the first 14 days. This is followed by one 400 mg Virolans XR® tablet once a day, together with other HIV medicines. Children 6 to 17 years of age with a body surface area of 1.17 square meter (m2) or greater—Dose is based on body size and must be determined by your doctor. The starting dose is usually 150 milligrams (mg) per square meter (m2) of Virolans® oral suspension or tablets for the first 14 days. This is followed by 400 mg of Virolans XR® once a day, together with other HIV medicines. Children younger than 6 years of age with a body surface area of less than 1.17 m2—Use is not recommended. For oral dosage forms (suspension or tablets): Adults—200 milligrams (mg) once a day for 2 weeks, followed by 200 mg 2 times per day, together with other medicines. Children and infants 15 days of age and older—Dose is based on body size and must be determined by your doctor. Infants younger than 15 days of age—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store Virolans tablets or oral powder at room temperature between 68-77 degrees F (20-25 degrees C). Keep Virolans in the original container. Do not use Virolans if the seal over the bottle opening is broken or missing. Keep the bottle tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Virolans are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of nevirapine in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems which may require caution and an adjustment in the dose for patients receiving nevirapine.

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Cardiovascular disease is common in end-stage renal disease patients and accounts for more than half of the mortalities. Clinical, laboratory, and histopathological features comprise a schema that excludes conditions mimicking NSF while facilitating its reproducible and accurate diagnosis, even among physicians with little prior clinical experience with this entity. An alternative but less tested explanation is that density-dependent disease from species-specific soil microbes drive the diversity-productivity relationship by increasing disease and thus decreasing productivity at low diversity. This study investigates the utility of the breathing reserve index at the anaerobic threshold (BRIAT), which is defined as minute ventilation at the anaerobic threshold (AT)/maximum voluntary ventilation (MVV), to distinguish ventilatory-limited (VL) CF patients from nonventilatory-limited (NVL) CF patients. To evaluate the effect of long-term weight loss maintenance on arterial compliance, and metabolic and inflammatory parameters in obese patients who participated in a 6-month weight loss program featuring nutritional and exercise intervention. An electron microscopic study of the renal polkissen cells revealed evidence of their participation in the renin angiotensin system. Based on the expected probabilities, observed to expected (O/E) ratios for each outcome, after each of the 3 procedures, were calculated for each hospital. Preliminary Monte Carlo study of (18)F-FDG SPECT imaging with LaBr(3):Ce Crystal-based Gamma Cameras.

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Mutational covariances between three life-history traits are shown to exhibit a weak pattern of decline with increasing population size (increasing selection), while the orientation of mutational matrices remains reasonably constant. These results demonstrate that interactions between direct and socially mediated effects of past environments influence life history evolution in size-structured and stage-structured populations. We separated the component spatial patterns of frequency-dependent absorption in chemicals and frequency-independent components such as plastic, paper, and measurement noise in terahertz (THz) spectroscopic images, using known spectral curves. A highly selective fluorescent probe for pyrophosphate detection in aqueous solutions. The principle can be used not only in detecting human respiratory impedance, but also in detecting the bio-impedance of other human organs.

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Papillary muscle dyssynchrony may predict the response of cardiac resynchronization therapy on the regression of functional mitral regurgitation and may suggest the suitable therapeutic options, such as cardiac resynchronization therapy, mitral valve repair, coronary revascularization separately or in combination. Intestinal protein exudation was studied during the treatment by means of of 131I-albumin. Hyperglycemic responses to dopamine (DA), noradrenaline (NA), adrenaline (A) and isoprenaline (ISP) were dose-related and accompained by a depletion of liver glycogen. On the more insidious manifestations of bias in scientific reporting. Kinetics of photoirradiation-induced synthesis of soy oil-conjugated linoleic acid isomers. Some why can you not take alcohol with flagyl unknown up to now physiological factors (motivation, attention?) may be critical for these phenomena.

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Kinetic phases of distribution and tumor targeting by T cell receptor engineered lymphocytes inducing robust antitumor responses. Bursopeptide-1 stimulated expression of B cell differentiation antigens in lymphocyte culture from patients with burns. Optic nerve involvement is a rare side effect of isoniazid (INH) and has not been described in children. Rats treated with diamox tablet 250 mg uses nitrous oxide exhibited a marked decrease in the rate of oxidation of formate to carbon dioxide. CD81 strengthens multivalent VLA-4 contacts within subsecond integrin occupancy without altering intrinsic adhesive properties to low density ligand. Forty-eight hours after anastomosis, enhanced reactivity of contralateral pulmonary arteries is attributable in part to increased lipoxygenase products as opposed to nitric oxide or other eicosanoid products. The results in respect of their potency test were found to conform to official pharmacopoeias (B.P. Possible Acid Rain Woes in the West: Damage is not evident as yet, a new report says, but there are plenty of reasons to be worried. But the stepwise behavioral responses in different proportions of two organphosphorus pesticides were almost the same as each other, and the evident difference of the behavioral responses time was not detected. High producing cell lines, suitable for cGMP manufacturing, were identified.

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