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Prostin is used to treat erectile dysfunction (impotence) and to help diagnose certain causes of this disorder. Prostin is also used to improve blood flow in newborn babies with heart problems. This medication guide addresses only the adult male use of Prostin in erectile disorders.

Other names for this medication:
Alpostin, Caverject, Edex, Muse, Prostin, Vitaros

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Also known as: Alprostadil


Prostin urethral suppository is used to treat men who have erectile dysfunction (also called sexual impotence). It belongs to a group of medicines called vasodilators that can increase blood flow by expanding blood vessels. Prostin causes an erection because it increases the blood flow to the penis.

Prostin should not be used as a sexual aid by men who do not have erectile dysfunction. If the medicine is not used properly, permanent damage to the penis and loss of the ability to have erections could result.

Prostin is available only with your doctor's prescription.



If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: fainting, painful/prolonged erection.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store unopened foil pouches in the refrigerator. Keep the medicine away from heat. It may not work if exposed to temperatures above 30 degrees C. You may also store the suppositories at room temperature for up to 14 days before each use.

Detailed Prostin dosage information

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The most common side effects associated with Prostin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use Prostin suppositories if you have a penile implant unless advised by doctor.

Use a condom when having sexual intercourse with a pregnant female while using this medicine. Although harm to the fetus is unlikely, using a condom will protect the fetus from exposure to this medicine. If a woman can become pregnant, use of contraceptive methods is recommended because the effects of this medicine on early pregnancy are not known.

This medicine may make you dizzy or lightheaded. Do not drive or do anything that could be dangerous until you know how this medicine affects you.

If too much is used, the erection lasts too long and does not reverse when it should. This condition is called priapism. If the erection is not reversed, the blood supply to the penis may be cut off and permanent damage may occur.

Contact your doctor immediately if the erection lasts longer than 4 hours or if it becomes painful. This may be a sign of priapism and must be treated right away to prevent permanent damage.

This medicine will not prevent pregnancy or protect you or your partner from diseases such as syphilis, herpes, or HIV. Use a latex condom during sex for protection.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

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