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Compazine (Prochlorperazine)

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Compazine is a synthetic propylpiperazine derivative of phenothiazine with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Compazine antagonizes the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis.

Other names for this medication:
Bukatel, Compro, Emidoxyn, Eminorm, Ingametil, Meditil, Neurocin, Neurograin, Neurolice, Neuromol, Neuronit, Novapar, Nuroflow, Nuropar, Prochlorperazine, Procomp, Psygrain, Stemetil, Swigrain, Vasograin, Vertipro, Vestil

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Also known as: Prochlorperazine


Generic Compazine is taken for controlling severe nausea and vomiting and treating schizophrenia. It is also used for the short-term (4 weeks) treatment of generalized nonpsychotic anxiety. It may also be used for other conditions. Generic Compazine is a phenothiazine. It works by blocking a certain chemical (dopamine) in the brain. Compazine is also known as Prochlorperazine, Compro, Stemetil, Stemzine. Generic name of Generic Compazine is Prochlorperazine. Brand name of Generic Compazine is Compazine.


Take Generic Compazine by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation. If you want to achieve most effective results do not stop taking Generic Compazine suddenly.


If you overdose Generic Compazine and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Compazine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of prochlorperazine in children 2 years of age and older or weighing 9 kilograms (kg) (20 pounds (lbs)) and over. Use in children younger than 2 years of age or weighing under 9 kg (20 lbs) is not recommended.

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Lopinavir/ritonavir monotherapy as a nucleoside analogue-sparing strategy to prevent HIV-1 mother-to-child transmission: the ANRS 135 PRIMEVA phase 2/3 randomized trial. Five years before the onset of bleeding the patient had had an abdominal hysterectomy that may have seeded the adjacent vesical and small bowel tissue. The anterior tibia insertion was defined as 15 mm lateral from the medial tibia edge and 45 mm below the medial tibia joint line. However, computer modelling provides an exciting new approach to overcome these restrictions and offers new insights into uterine activation during term and preterm labour. Structurally diverse chaetophenol productions induced by chemically mediated epigenetic manipulation of fungal gene expression. Embedding sulfur in MOF-derived microporous carbon polyhedrons for lithium-sulfur batteries. Hydrogen bonding versus stacking stabilization by modified nucleobases incorporated in PNA.DNA duplexes. Genome-wide information allowed us to identify one region on chromosome 13 associated with inbreeding depression. Given the unknown consequences of anaesthetics on neurodevelopmental outcomes, minimising the exposure of this population to such agents may have long-term benefits.

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Blood serum samples from 60 cancer patients and 49 controls were analyzed for serum MACC1 by ELISA. Platelet-endothelial cell adhesion molecule-1 gene polymorphism and its soluble level are associated with ischemic stroke. Many costly studies do not even yield interpretable results as to whether the mechanism being pursued has therapeutic potential. In 14 out of 62 cases the septa amoung the cartilaginous lobes were filled with blood. Compared to the nanoscale DCB-rich vesicles, the DCP-rich vesicles have smaller size, higher negative zeta potential, higher main transition temperature, and better storage stability. Treatment of Iatrogenic Pseudoaneurysms Using Ultrasound-Guided Thrombin Injection over a 5-Year Period. Ten patients suffering from degenerative arthropathies were treated to demonstrate a significant influence of suppositoroes containing 500 mg mucopolysaccharide polysulfuric acid ester on certain clotting parameters such as plasma recalcification time, partial thromboplastin time and thrombin time. Women with gestational proteinuria had greater body-mass index and higher blood pressure at study enrollment. Excess adipose tissue and different hormonal substances possibly play a significant role in this complex obesity-related carcinogenesis. RBC AChE is raised than normal level in patients suffering from PDD, where AChE inhibitors are helpful.

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Ovarian hyperstimulation syndrome (OHSS) is a potentially life-threatening complication of ovarian stimulation associated with severe vascular hyperpermeability. In this review we focus on new applications that have successfully cultivated previously uncultivated bacteria. Intermittent high-dose cyclophosphamide with and without prednisolone: a study of the relationships between toxicity, response and survival in metastatic lung cancer. Information from eligible studies was abstracted using a standardized checklist. Diabetic vascular complications (DVCs) affecting several important organ systems of human body such as cardiovascular system contribute a major public health problem. Folding and maturation of many secreted proteins depend on a single extracellular foldase, the PrsA protein. Pharmacogenetic information will enable the use of a personalized approach to the asthma management which will adjust the therapy technology and increase the possibility of achieving disease control.

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Analysis of the contribution of the road traffic industry to the PM2.5 emission for different land-use types. Because CACNA1C is not only a crucial gene in normal brain function but also a promising candidate risk gene for psychiatric disorders such as bipolar disorder and schizophrenia, elucidating the molecular basis of transcriptional regulatory mechanism will be critically important. Intensity stability and wavelength correlations of near-infrared supercontinuum generation are studied in all-normal flattened dispersion, all-solid soft glass photonic crystal fiber. The role of the veterinarian in industrialized chicken and egg production. Evolution of oligomeric state through allosteric pathways that mimic ligand binding. Evaluation of survival benefits by platinums and taxanes for an unfavourable subset of carcinoma of unknown primary: a systematic review and meta-analysis. The low (between 0.1 and 1 per thousand) delta15N values imply N2-fixation by cyanobacteria, and the decrease in delta13C values up-core represent the effect of sewage input and land based runoff, or possible contribution from microbial biomass. After down-regulating CDK2-AP1 in breast cancer cells, the cell cycle was accelerated and cell proliferation enhanced.

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GBP is associated with an increased risk of post-operative deficiency in some vitamin K-dependent coagulation factors. In order to inhibit complement activation initiated by the classical pathway (CP), we used streptococcal M protein-derived peptides that specifically bind human C4BP, an inhibitor of the CP. The abortion rates of nonwhites were more sensitive to distance than those of whites. Potential to improve outcomes: causes of 30-day readmission after cardioverter defibrillator implantation. A new dual-functional electrochemical biosensor for the detection of prostate specific antigen (PSA) and telomerase activity was successfully developed based on a sandwich immunobinding format and telomerization assisted hemin-G-quadruplex-based DNAzyme as a biolabel. A common upper airway and digestive tract is a rare congenital anomaly that is usually fatal and its exact incidence is not known. 39 patients with insulin-treated diabetes (18 type 1, 21 type 2 diabetes) were exposed to mental stress by means of a 2 h-driving training.

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MicroRNAs 373 and 520c are downregulated in prostate cancer, suppress CD44 translation and enhance invasion of prostate cancer cells in vitro. The levels of incriminated colonic bacterial enzymes are increased by dietary fat and inhibited by certain dietary fibers. Recently discovered small noncoding molecules, microRNAs (miRs), in body fluid seem promising to be utilized as a biomarker to monitor DM initiation and progression, as it is believed that expression of circulating miRs reflects disease pathology. Ion-specific modulation of protein interactions: anion-induced, reversible oligomerization of a fusion protein. During the Meiji era, at the end of the 19th century, Japan introduced western systems into many fields, economically developing later than other industrially developed countries. Bacterial culture of apheresis platelets: a mathematical model of the residual rate of contamination based on unconfirmed positive results. Control of the microbiological laboratories of phthisiopulmonological centers.

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Although specific guidelines for neonates are often lacking, antibiotic stewardship principles can be applied to the neonatal intensive care unit. Spherical particles were produced by droplet-to-particle conversion of droplets. Excessive exposure to Al may result in increased Al body burden and impaired bone formation and mineralization, leading to bone disease. The Vibrionaceae frequently possess a life history cycle where bacteria are attached to a host in one phase and then another where they are free from their host as either part of the bacterioplankton or adhered to solid substrates such as marine sediment, riverbeds, lakebeds, or floating particulate debris. A 25-residue elongation at the N-terminus endows parvulin 17 (Par17) with altered functional properties compared to parvulin 14 (Par14), such as an enhanced influence on microtubule assembly. Clinical characteristics of severe supracondylar humerus fractures in children. In this study, we annotated individual genes downstream of TBR1 and investigated any associations with ASDs through extensive literature searches.

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As such, it provides a unique genetic resource for plant cell wall degrading microbial enzymes that could be used in the production of biofuels. The two Bayesian models were compared with a restricted maximum likelihood (REML) approach using a genomic relationship matrix. Point-of-care (POC) devices are increasingly being used at the bedside in perioperative patient management of hemostatic function. Though brown rice (BR) and germinated brown rice (GBR) have high antioxidant potentials as a result of their bioactive compounds, reports of their effects on oxidative stress-related conditions such as type 2 diabetes are lacking. This procedure--called Dualanaesthesia how long does flagyl work after last dose --is simple and of low risk. Proliferative glomerulonephritis with monoclonal IgG deposits (PGNMID) is a rare and recently identified disease with a poor prognosis irrespective of the treatment. ABO antibody levels are reduced more effectively by group AB FFP than by albumin. In systemic salmonellosis, macrophages constitute a niche for the proliferation of bacteria within the host organism. Biochemical studies of children with the syndromes of autism, childhood schizophrenia and related developmental disabilities: a review.

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Characterization and cDNA cloning of phospholipase C-gamma, a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. The prevalence of 12-bp insertion in cagA in Okinawa and the United States (U.S.) was examined by DNA sequencing. Although the immediate postoperative recovery period was uneventful, rectal bleeding and signs of haemorrhagic shock developed within 10 hours of surgery. The Mediterranean tradition offers a cousine rich in colors, aromas and memories, which support the taste and the spirit of those who live in harmony with nature. TFClass: an expandable hierarchical classification of human transcription factors. Donors in both conditions completed a series of questions to assess anxiety, experience of prefaint reactions, and willingness to provide a future donation. Sixty-two patients converted to AD over a mean follow-up of 1.43 years. Radiation pretreatment does not protect the rat optic nerve from elevated intraocular pressure-induced injury. Here we demonstrate that beta-arrestin-2 mediates anti-apoptotic cytoprotective signaling stimulated by a typical 7-transmembrane receptor the angiotensin ATII 1A receptor, expressed endogenously in rat vascular smooth muscle cells or by transfection in HEK-293 cells. The significant contribution of disulfide bonds to the conformational stability of proteins is generally considered to result from an entropic destabilization of the unfolded state causing a faster escape of the molecules bactrim antibiotic mayo clinic to the native state.

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Current healthcare in Bulgaria: time for predictive diagnostics and preventive medicine. Women were significantly more affected than men in shoulders, wrists/hands, upper back, lower back, and ankle/feet. although this study does not establish any clinical relevance of removing more or less bone at primary TKA, its results suggest that if a PS design is indicated, it is preferable to select a model which resects less distal femoral bone. Odour sweetness increased regardless of PROP taster or sweet liker status. To examine the association of serum lipids, inflammation and seropositivity on coronary heart disease (CHD) and stroke in patients with rheumatoid arthritis (RA). A number of factors contribute to this, and methods to overcome the barriers to insulin therapy need to be sought. Dose-response functions in carcinogenesis and the Weibull model. Using painful nociceptive-selective laser stimuli to the hand, and phase-encoded functional magnetic resonance imaging analysis methods, we observed somatotopic maps of the digits in contralateral SI. A case of extensive carcinoidosis of the small intestine with cardiopathy.

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A rapid microtechnique for the preparation of biological material for the simultaneous analysis of calcium, magnesium and protein. Estimation of total muscle in live cattle using ultrasonic measurements. EtOH treatment and miR-9 knockdown resulted in similar cranial defects including microcephaly. Our results suggest that the Ia-positive keratinocytes can serve as target cells in skin rejection of limb allografts. Iron acquisition is an important aspect of the host-pathogen interaction. Hypoplastic tibiae with postaxial polysyndactyly in two sibs: further conformation of a new syndrome. In this update an additional study that compared PN and Glutamine versus standard PN showed that the certain benefits of parenteral nutrition with added glutamine compared to standard PN for reducing hospital stay are no longer definite.

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Localization of renin in trophoblasts in human chorion laeve at term pregnancy. The breathing test was performed until the subject was unable to generate this Pdi. Identification and Characterization of the SnTox6-Snn6 Interaction in the Parastagonospora nodorum-Wheat Pathosystem. We recently demonstrated that murine T cells are capable of recognizing an enterovirus group antigen. Recommendations for genetic testing and management of individuals genetically at-risk of cutaneous melanoma. The beneficial effect of nonselective beta-blockers (NSBB) has recently been questioned in patients with end-stage cirrhosis. Phylogenetically terminal clades of East Asian mtDNA haplogroups C and D and Y-chromosome haplogroups N1c, N1b and C3, constituting the core of the gene pool of the native populations from Sakha, connect Sakha and South Siberia.

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