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Brosol (Albuterol)
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Brosol

Brosol is used to prevent and treat wheezing and shortness of breath caused by breathing problems. Brosol belongs to a class of drugs known as bronchodilators. It works by relaxing the muscles around the airways so that they open up and you can breathe more easily.

Other names for this medication:
Accuneb, Aerotide, Ancoril, Asthalin, Brolax, Bronkonat, Bronsim, Brorex, Codex, Derihaler, Durasal, Eascof, Elkof, Esmasol, Exporil, Hycoril, Kofnil, Pencolin, Pherin, Proventil, Salbomin, Salbrosin, Salbu, Salcare, Servent, Somavent, Suprivent, Ventidil, Ventosol, Ventosym, Ventsolv, Viburil, Vifex, Vospire, Xputum, Zerfy

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Also known as: Albuterol

Description

Albuterol is used to treat bronchospasm or wheezing in patients with reversible obstructive airway disease, such as asthma.

Albuterol belongs to the family of medicines known as adrenergic bronchodilators. Adrenergic bronchodilators are medicines that open up the bronchial tubes (air passages) in the lungs. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain albuterol. It may not be specific to Brosol Inhaler. Please read with care.

Use this medicine only as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered. Also, do not stop using this medicine or any asthma medicine without telling your doctor. To do so may increase the chance for breathing problems.

The albuterol inhalation solution (eg, Accuneb®) should be used with a jet nebulizer that is connected to an air compressor with good air flow. The inhalation solution and nebulizer will come with patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions.

To use the inhalation solution in the nebulizer:

Use one container of solution or mix the exact amount of solution using the dropper provided for each dose. Place the inhalation solution in the medicine reservoir or nebulizer cup on the machine. Connect the nebulizer to the face mask or mouthpiece. Use the face mask or mouthpiece to breathe in the medicine. Use the nebulizer for about 5 to 15 minutes, or until the medicine in the nebulizer cup is gone. Clean all the parts of the nebulizer after each use.

The albuterol inhalation aerosol (eg, ProAir® HFA, Proventil® HFA) and albuterol inhalation powder (eg, ProAir® Digihaler™, ProAir® Respiclick®) are used with a special inhaler that comes with patient instructions. Read the directions carefully before using this medicine. If you or your child do not understand the directions or are not sure how to use the inhaler, ask your doctor to show you what to do. Also, ask your doctor to check regularly how you or your child use the inhaler to make sure you are using it properly.

To use the inhalation aerosol:

The inhaler should be at room temperature before you use it. Insert the metal canister firmly and fully into the actuator. This actuator should not be used with other inhaled medicines. Remove the cap and look at the mouthpiece to make sure it is clean. Point the inhaler away from your face. Shake the inhaler well and test spray it in the air 3 times for ProAir® HFA or 4 times for Proventil® HFA before using it for the first time or if the inhaler has not been used for more than 2 weeks. To inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece just in front of your mouth with the canister upright. Open your mouth and breathe in slowly and deeply (like yawning), and at the same time firmly press down once on the top of the canister. Hold your breath for about 10 seconds, then breathe out slowly. If you are supposed to use more than one puff, wait 1 minute before inhaling the second puff. Repeat these steps for the second puff, starting with shaking the inhaler. When you have finished all of your doses, rinse your mouth with water and spit the water out. Clean the inhaler mouthpiece at least once a week with warm running water for 30 seconds, and air dry it completely. If you need to use the inhaler before it is completely dry, shake off the excess water, replace the canister, and spray it 2 times in the air away from the face. Use your regular dose. After using the inhaler, wash the mouthpiece again and dry it completely. If the mouthpiece becomes blocked, washing it will help. The Proventil® HFA inhaler has a window that shows the number of doses remaining. This tells you when you are getting low on medicine. The counter will turn red when there are only 20 doses left, to remind you to refill your prescription.

To use the inhalation powder:

Take the inhaler from the foil pouch before you use it for the first time. The inhaler provides about 200 inhalations. The dose counter will change to red when there are "20" doses left. Call your doctor or pharmacist for a refill of prescription or medicine. Make sure the cap is closed before using this medicine. Do not open the cap unless you are going to use it. Hold the inhaler upright as you open the cap fully until you hear a "click". Your inhaler is now ready to use. To inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece fully into your mouth and close your lips around it. Breathe in through your mouth as deeply as you can until you have taken a full deep breath. Do not block the vent above the mouthpiece with your lips or fingers. Hold your breath for about 10 seconds or as long as you comfortably can. Remove the inhaler from your mouth and check the dose counter to make sure you received the medicine. Close the cap firmly over the mouthpiece after using the inhaler. Always close the cap after each use. If you are supposed to use more than one puff, repeat these steps for the second puff, starting with opening the cap fully. Do not use a spacer or volume holding chamber together with the ProAir® Digihaler™. Keep the inhaler clean and dry at all times. Do not wash or put any part of the inhaler in water. Replace the ProAir® Digihaler™ if it has been washed or placed in water. If you need to clean the mouthpiece, wipe it gently with a dry cloth or tissue.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For inhalation aerosol dosage form (inhaler): For treatment or prevention of bronchospasm: Adults and children 4 years of age and older—Two puffs every 4 to 6 hours as needed. Children younger than 4 years of age—Use and dose must be determined by your child's doctor. For prevention of exercise-induced bronchospasm: Adults and children 4 years of age and older—Two puffs taken 15 to 30 minutes before exercise. Children younger than 4 years of age—Use and dose must be determined by your child's doctor. For inhalation powder dosage form (inhaler): For treatment or prevention of bronchospasm: Adults and children 4 years of age and older—Two puffs every 4 to 6 hours as needed. Children younger than 4 years of age—Use and dose must be determined by your child's doctor. For prevention of exercise-induced bronchospasm: Adults and children 4 years of age and older—Two puffs taken 15 to 30 minutes before exercise. Children younger than 4 years of age—Use and dose must be determined by your child's doctor. For inhalation solution dosage form (used with a nebulizer): For prevention of bronchospasm: Adults and children older than 12 years of age—2.5 milligrams (mg) in the nebulizer 3 or 4 times per day as needed. Children 2 to 12 years of age—0.63 to 1.25 mg in the nebulizer 3 or 4 times per day as needed. Children younger than 2 years of age—Use and dose must be determined by your child's doctor.

Overdose

If you overdose Brosol and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep the medicine in the foil pouch until you are ready to use it. Store at room temperature, away from heat and direct light. Do not freeze.

Store unopened vials of this medicine at room temperature, away from heat and direct light. Do not freeze. An open vial of medicine must be used right away.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the canister at room temperature, away from heat and direct light. Do not freeze. Do not keep this medicine inside a car where it could be exposed to extreme heat or cold. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Store Proventil® HFA inhaler with the mouthpiece down.

Throw away the ProAir® Digihaler™ or ProAir® Respiclick® 13 months after opening the foil pouch, when the dose counter reaches "0", or after the expiration date, whichever comes first.

Detailed Albuterol dosage information

Side effects

The most common side effects associated with Brosol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Aging is associated with a number of events at the molecular, cellular and physiologic levels that influence carcinogenesis and subsequent cancer growth. A negative or diminished reflex during early infancy is often a sensitive indicator of spasticity. Time-activity curves generated from regions of interest placed over the cerebral hemispheres, AVMs and/or various venous structures permitted, respectively, estimation of interhemispheric partition of perfusion, estimation of the fraction of total cerebral hemispheric perfusion preferentially directed into a malformation, and indication of the route of venous drainage from the lesions. Consistent with this role, we show that Mus81-Eme1 is required for generating meiotic crossovers. Stimulation of right stellate ganglion, craniovagal, and right stellate cardiac nerves produced localized shortening on the right atrium, particularly at the sinus node area, and invariably induced sinus tachycardia. In vitro studies of dissociated neurons have demonstrated that axons are initiated from a nonpolarized stage. Characteristics of hemodynamic reactions during various endoscopic surgeries for cholelithiasis in patients with concurrent cardiovascular pathologies. At the onset of electronic overlap the empirical values deviate from the reference values considerably. Quantitative assessment of the sensitivity of various commercial reverse transcriptases based on armored HIV RNA. All heterofibrins possess a diyne-ene moiety, while the monolactyl and dilactyl moiety featured in selected heterofibrins is unprecedented in the natural products literature.

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Urodynamic and haemodynamic effects of a single oral administration of ephedrine or phenylpropanolamine in continent female dogs. These findings are consistent with the proposed role of calbindin-D28k in photic signaling in the suprachiasmatic nucleus,(32) and point to the possibility that suppression of calbindin-D28k expression is linked to the mechanism by which constant light disrupts circadian rhythms. Dok adapter proteins have been primarily implicated in negative regulation of tyrosine kinase signaling, but Dok-4 has been reported to exert both inhibitory and stimulatory effects. All these effects, especially frozen soil and snowpack, make great challenges to watershed scale hydrologic and nonpoint-source pollution models simulation in cold climate. Use of citric or lactic acids in combination with ammonium hydroxide gave a protectant solution with high pH (resulting in effective crosslinking between trehalose and borate) but a dry product with reduced pH upon rehydration (conducive to cell survival).

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However, its expression was markedly diminished in seminomas, embryonal cell carcinomas, and in mixed germ cell is flonase an otc drug tumors, at both transcriptional and translational levels. Decay of epidermal and dermal structures within skin flap tissue was paralleled by an immune cell-mediated expression of chemokines (macrophage inflammatory protein 2, macrophage chemoattractant protein 1), cyclo-oxygenase (COX) 2 and inducible nitric oxide synthase (iNOS). Habitat and year-to-year variation in haemoglobin concentration in nestling blue tits Cyanistes caeruleus. Moreover, these choices are subtractions from, or contributions to, the pure public good of air quality. Patients frequently fail to receive adequate pain relief from, or are intolerant of, first-line therapies prescribed for neuropathic pain (NeP). Little information is available pertaining to the results after implantation of prolonged fresh grafts.

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